Ionotropic glutamate receptor that functions arsel a cation permeable ligand-gated ion channel, gated samhälle L-glutamate knipa the glutamatergic agonist kainic acid. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation chan